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>>>>>>> d80cd8fa3e1fb5461144707ba04f7385ec6726a7:2011/02/synteny-relevant-links/index.html
Contents:
- Information
- On-line comparative sequenced genome databases
- Synteny downloadable programs
- A few multiple alignment programs
Information
On-line comparative sequenced genomes databases
Database |
Species;graphics;computation |
Publication |
Phytozome |
Plants; Genome browsers; |
Hartmann et al. 2006 |
PLAZA |
Plants; Gene region alignments, Dotplot, Chromosome alignment, Multiplicon; blastp & OrthoMCL method |
Proost et al. 2009 |
Plant Genome Duplication |
Plants; Dotplots and detail; blastp & MCSCAN |
Tang et al. 2008 |
Gramene |
Grasses; Ensembl; |
Liang et al. 2008 |
Legume Information System |
Legumes; CMap; |
– |
JGI genome projects |
Various; Vista and links to Phytozome; |
– |
Vista |
Various; Java display of regions; Shuffle-LAGAN & BLAT in pipeline, allows user input. |
Frazer et al. 2004 |
Narcisse |
Various; Dotplots, circos, chromosome-based gene alignment; blastp & custom script. |
Courcelle et al. 2008 |
Cinteny |
Various; Genome/chromosome view; custom algorithm |
Sinha & Meller 2007 |
CoGe |
Various; Dotplot (SynMap) and ajax Genome Browser; DAGchainer, Blast |
Lyons & Freeling 2008 |
OrthoClusterDB |
No plants; Genome chromosome view, link to Gbrowse; OrthoCluster, allows user input. |
Ng et al. 2009 |
The Synteny Database |
No plants; Various views; Blastp & custom pipeline, emphasis on duplications and ohnologs. |
Catchen et al. 2009 |
Ensembl |
No plants; ComparaMart, DAS visualization; TreeBeST, Pecan. |
Hubbard et al. 2009 |
UCSC Genome Browser |
No plants; |
Miller et. al. 2007 |
Inparanoid |
Various, produce lists of orthologs |
Ostlund et al. 2009 |
OrthoMCL |
Various, produce lists of orthologs |
Li et al. 2003 |
Synteny Computation and/or Display Software
Key: Perfect - conserved order in block, Imperfect - allows micro-rearrangments in block, Duplications - allows duplicated regions, Multiplicon - mutually homologous segment between >2 genomes.
Software |
Input |
Synteny |
Graphics |
Publication |
i-ADHoRe |
N gene lists |
Perfect, duplications, multiplicon |
Generates plots using Perl GD |
Vandepoele et al. 2002 Simmillion et al. 2007 |
AXTCHAIN |
BLASTZ alignments |
|
|
Kent et al. 2003 |
DiagHunter |
Similarity file |
Imperfect |
GenoPix Tcl/Tk |
Cannon et al. 2003 |
GRIMM-synteny |
Similarity file |
Imperfect, breakpoints |
Web |
Tessler 2002 andPevzner and Tessler 2003 |
FISH |
Ordered marker file per contig and pairs files |
Imperfect |
no |
Calabrese et al. 2003 |
DAGchainer |
Gene pairs with chromosome positions |
Perfect |
Dot plot |
Haas et al. 2004 |
ColinearScan |
Protein sequences with positions and pairs file |
Perfect, estimates gap parameters. |
no |
Wang et al. 2006 |
OSfinder |
Homologous markers with locations (provide scripts to generate this file from different sources) |
Perfect, estimates all parameters, no duplication |
PNG file of blocks and of dotplot |
Hachiya et al. 2009 |
OrthoCluster |
Imperfect |
|
|
Vergara & CHen 2009 |
Cyntenator |
guided tree & similarity files |
Conserved synteny between n genomes |
no |
Rodelsperger & Dieterich 2010 |
Mauve |
Multiple sequences (small genomes or regions) |
Conserved, aligns multiple sequences, computes synteny & breakpoints |
Java graphics & manager |
Darling et al. 2004 |
MCMuSeC |
Homologs for multiple genomes & phylogenetic tree |
Detects gene clusters |
no |
Ling et al. 2009 |
MCscan |
blast & gff file |
DAGchainer + consensus sequence builder |
no |
Tang et al. 2008 |
LineUp |
Genetic maps |
|
no |
Hampson et al. 2003 |
GenomeMatcher |
BLAST, MUMmer |
no |
Dotplots and closeup (seegallery) |
Ohtsubo et al. 2008 |
CMap |
Maps (genetic, FPC, sequence) |
no |
Perl/CGI (seescreen shots) |
Youens-Clark et al. 2009 |
GBrowse_syn |
Alignments |
no |
Perl/CGI GBrowse-based |
- |
Circos |
GFF files |
no |
Perl/CGI |
Krzywinski et al. 2009 |
A few alignment programs
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